Over 18 years: patches should be worn during waking hours (approximately 16 hours) and removed at bedtime. Apply to clean, dry intact areas of hairless skin. The same site should not be used on consecutive days. Smoking and vaping cessation: Most smokers and vapers should start with one 25mg patch per day for 8 weeks, followed by one 15mg patch per day for 2 weeks then one 10mg patch per day for 2 weeks. Those who smoke fewer than 10 cigarettes a day or vape infrequenty or use low-strength e-liquid (light to moderate vapers) should start on one 15mg patch per day for 8 weeks followed by one 10mg patch per day for 4 weeks. Those who experience excessive side-effects with the 25mg patch that do not resolve within a few days should change to the 15mg patch for the remainder of the 8-week course, before stepping down to the 10mg patch for 4 weeks. If symptoms persist, advice from a health professional should be sought. Cutting down prior to quitting: starting dose as above. Those starting on the 25mg patch should transfer to the 15mg patch as soon as cigarette consumption reduces to less than 10 cigarettes per day or vaping dependency decreases. A quit attempt should be made as soon as

Over 18 years: patches should be worn during waking hours (approximately 16 hours) and removed at bedtime. Apply to clean, dry intact areas of hairless skin. The same site should not be used on consecutive days. Smoking and vaping cessation: Most smokers and vapers should start with one 25mg patch per day for 8 weeks, followed by one 15mg patch per day for 2 weeks then one 10mg patch per day for 2 weeks. Those who smoke fewer than 10 cigarettes a day or vape infrequenty or use low-strength e-liquid (light to moderate vapers) should start on one 15mg patch per day for 8 weeks followed by one 10mg patch per day for 4 weeks. Those who experience excessive side-effects with the 25mg patch that do not resolve within a few days should change to the 15mg patch for the remainder of the 8-week course, before stepping down to the 10mg patch for 4 weeks. If symptoms persist, advice from a health professional should be sought. Cutting down prior to quitting: starting dose as above. Those starting on the 25mg patch should transfer to the 15mg patch as soon as cigarette consumption reduces to less than 10 cigarettes per day or vaping dependency decreases. A quit attempt should be made as soon as possible. Those who have reduced to less than 10 cigarettes a day should use the 15mg patch for 8 weeks and decrease to 10mg for the final 4 weeks. When vapers have reduced their dependency sufficiently, they should use the 15 mg patch for 8 weeks and then step down to 10 mg for the final 4 weeks. Temporary abstinence of more than 16 hours: smokers of 10 or more cigarettes per day and heavy vapers: 25mg patch; fewer than 10 cigarettes a day and light to moderate vapers: 15mg patch. Adolescents 12-18 years: as per adults. If treatment longer than 12 weeks is required, advice from a health professional should be sought.